St Anne’s is the home of choice for the brightest and most ambitious students, including those from underrepresented groups.
St Anne’s is one of Oxford’s largest colleges, with over 800 students. Our Fellows’ world leading research ranges across the arts, humanities, social sciences, mathematics, and physical, life and medical sciences.
Our diverse, inclusive community extends around the globe through our alumnae, who build on their experiences here to change the world for the better.
Situated within 5 acres of tranquil leafy grounds, St Anne’s enjoys a unique atmosphere in which to hold any conference, dinner or special event.
Writing your personal statement can be daunting – for many university applicants it might be their first time preparing a formal summary of their academic achievements, and that can often feel boastful or uncomfortable – where should you even begin?
Our current students have very kindly given us permission to publish some of their personal statements to help give you some suggestions as to how to structure your personal statement. Most importantly, these personal statements are by no means perfect, but they earned these students their places at the University of Oxford, and therefore your personal statement doesn’t have to be perfect either.
Please note that the majority of these personal statements were written before the changes to the personal statement in 2025 and are therefore not reflective of the new, three part structure. However, the content will still be useful for a current application.
Academic year application was made: 2022-23
What attracts me to biochemistry is the potential to explore the molecular intricacies that uphold life in all its forms. I find it compelling how the closer I look into a certain function, the more complex it becomes. Learning about immunology in A-Level biology piqued my initial interest in biochemistry, as I questioned how communication between cells occurs. This inspired me to read ‘Immune: A Journey into the Mysterious System that Keeps Us Alive’ by Philip Dettmer, which deepened my interest as I discovered the vast diversity of cells in the immune system. My previous perception of immune cells fighting pathogens was elevated to a sophisticated sequence of cells and molecules interacting to defend the body via initiation, propagation and termination of the immune response. I was also fascinated by the key role of proteins in the mechanisms of immune cells, such as signalling and response.
My research into proteomics led me to a podcast on protein structure and AI, where researchers discussed the development of an AI computer programme, AlphaFold2 (AF2): a breakthrough in predicting the 3D structure of proteins using existing data. The importance of this technological advance was stressed to me as I investigated protein structure further. I learned about Levinthal’s paradox, which illustrates the complexity of the protein folding problem and helped me to grasp the significance and potential of AF2. I gained an appreciation for the increasing relevance of bioinformatics in life science. It was also exciting to learn of the advances in molecular medicine that AF2 can lead to. I attended a taster lecture at Oxford focusing on physiological adaptations of the neuromuscular junction. A memorable segment looked at the crucial function of SNARE proteins in membrane fusion, and their importance in synapse transmission. I thought back to AF2’s discovery and how it can allow scientists to model these kinds of proteins more accurately. At university, I hope to delve further into the field of computational biochemistry and its future applications, such as advancements in drug development. It amazes me how understanding details of life on a molecular level can answer wider questions and help to solve real-life problems.
My interest in cells motivated me to engage in Gonville and Caius’ essay competition, answering the question “What are the logistical challenges of multicellularity and how do organisms overcome them?”. I enjoyed evaluating the pros and cons of organisms becoming multicellular, and the evolutionary stages that led to the unique range of life that we observe today. It revealed to me many advantages of unicellularity that I had not considered before, such as exchange with the environment and adapting to changing conditions. While researching single-celled organisms, I was struck by the simplicity of some of their structures and behaviours, leading me to question the borderline between living and non-living matter. I was inspired to read Prof. Paul Davies’ article titled “What is life?” which examines the philosophical and scientific debate surrounding matter and life. Aristotle took a teleological approach, while Schrodinger suggested that new laws of nature may be required to fully comprehend life. From a biochemist’s perspective, I would counter that life is a series of chemical reactions occurring within and between cells, evolved for sustenance and reproduction. It is this seemingly simple yet astonishingly complex idea which makes biochemistry so enthralling to me.
Aside from my studies, I’m also an active member of my community. In addition to volunteering and mentoring, I cultivated my leadership skills and initiative to celebrate diversity at my school by leading the organisation of our first ever Culture Week. Through this, I developed my teamwork and management skills, which are applicable in any lab setting. I was glad to make an impact at my school, and look forward to continuing to do so at university.
My interest in biochemistry began while I read an article on the dynamics of ssDNA hybridisation. The scientists achieved an extraordinary amount of detail when using TIRF imaging. They revealed the kinetics of independent strands and explained how these were affected by extrinsic factors with the Eyring equation. Their precision inspired me – chemical principles can be applied to produce a dynamic view of biological systems.The overlap between biology and chemistry highlighted the intricacies of the molecules which allow for life – all of which contain carbon. This special atom has the perfect number of electrons to have sp3 hybridised orbitals, lending it the ability to form 4 equal sigma bonds and long chains – a phenomenon known as catenation. When a lecture and supervision by Stewart Sage of Selwyn College, Cambridge presented the delicate subcellular pathways of osmoregulation, I was fixed on learning more about the chemistry of life. Having taken part in the Cambridge Chemistry Challenge, I enjoy being exposed to problems which at first seem challenging but can be solved by applying prior knowledge in elegant ways.I have been especially interested in methods with which enzymes carry out their functions. By gaining a detailed understanding of these mechanisms, we can seek to use the biological machinery to our advantage, as I saw when at the Royal Institution. I was tasked with using gel electrophoresis to compare DNA fragments from different group A Streptococci strains. After running the gel successfully, I understood that palindromic mutations in the fragments had acted as markers for the restriction enzymes, producing DNA bands which were identifiable with the ladder. When analysing the results, we were able to predict the severity of the infection, ranging from mild strep throat to necrotising fasciitis.The first section of MITx’s Molecular Biology MOOC, discussing DNA replication and repair, drew me more towards enzyme mechanics. I enjoyed learning about the structure of DNA polymerase and how its ‘fingers’ hold dNTPs in place using pi-stacking, interactions with other charged amino acids in the O-helix, and Mg2+ ions. Nucleotide tautomerisation also poses a threat to the accuracy of replication; therefore, the dienzyme contains a proofreading exonuclease, making the process 100 times more accurate. The overlap between mutation and apoptosis interested me; changes in the fine balance between bcl2 and Bax expressions could escalate to cell death, with bh3 mimetic drugs being used to combat this. I saw how problems in the biological field could be solved using chemistry.Articles on the pathophysiology of Parkinson’s and ARMD led me to read about iPSCs and their use in deriving specialised tissues in vitro – tissues which were used as organoids to study potential therapies for the diseases. After listening to Shinya Yamanaka’s lecture on the future of iPSCs, I was inspired to undertake an EPQ dissertation on the viability of iPSCs in precision medicine. During the research phase, I shadowed researchers in the UCL Institute of Ophthalmology, where I was trained in primer design, protein BLAST, western blots, genotyping murine lines, and PBMC isolation. Above all, I was able to speak to researchers in Prof. Pete Coffey’s lab about their work using a patient-derived iPSC organoid model. This led me closer to understanding how research was approaching to their use in medicine – the team had already developed a strong stem cell replacement therapy.I found an importance in self-study early as I taught myself the drums and guitar to a high level. This gave me a sense of accomplishment as I sought to imitate this in other impersonal interests. In college, I found it fulfilling to study ancient world literature, via a MOOC; stretching my interests in the arts, I read classical plays and joined a college poetry society. On my DofE Bronze expedition, I developed an interest in adventure sports, camping frequently since.
Academic year application was made: 2021-22
Used to also apply for: Medical Biosciences; Biochemistry
Used to also apply for: Geology
Used to also apply for: Mechanical Engineering
Academic year application was made: 2019-20
Used to also apply for: Liberal arts; Languages and cultures; Sociology
Academic year application was made: 2020-21
Used to also apply for: Theoretical Physics; Mathematics and Physics